Suyu has been taken down, for now anyways...

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MEKA is a multi-machine emulator for MS-Windows and GNU/Linux. It's known for emulating the Sega 8-bit systems very well and support the following machines: Sega Game 1000/3000/7000, Sega Mark III, Sega Master System, Sega Game Gear, ColecoVision (COLECO), Othello Multivision (OMV)...

PCSX2 is an open-source emulator using a combination of MIPS CPU Interpreters, Recompilers and a Virtual Machine through plugins to manage hardware states and PS2 system memory. It has been running for more than 10 years and can run over 2000 titles with many at full speed...
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